In vitro Evaluation of Polyphenol Rich Fraction of Ipomea batatas (Mother delight) Leaf Extract as Anti-inflammatory Agents and its LCMS Profile

  • *Musa Bashir, Ahmad Muhammad Yamani and Salisu Yahaya Mohammed

  • UJMR 2022, 7(1), Pp 120 - 128, DOI:  10.47430/ujmr.2271.018

Abstract

High intake of plant foods is associated with lower risk of chronic diseases as suggested by epidemiological evidence. This study aimed to investigate the anti-inflammatory potential of polyphenol rich fraction of Ipomoea batatas leaf extract and the compounds possibly responsible for the activity using LCMS. The anti-inflammatory studies were carried out in vitro by protein denaturation technique. The result shows significant different (p<0.05) percentage inhibition of denaturation 90.59% at 1000 μg/ml of the extract compared to the standard drug (declofenac) 95.12% at 1000 μg/ml. The LCMS profiling of the extract revealed the presence of many metabolites (polyphenols) such as chrogenic acid, myricetin, furocoumarinic acid, aromadendrin, naringenin, 4,5-dicaffeolquinic acid and abietinol among others. The presence of these metabolites could be the reason for the anti-inflammatory effect of the extract observed. This implies that the plant can be exploited for its medicinal, therapeutic properties and possibly used to reduce the risk of many chronic diseases.

Keyword: Anti-inflammatory activity, Protein denaturation technique, Mother delight, LCMS, Phytochemicals.

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The Editorial Board of UJMR is glad to have published the Twelfth edition (Volume 7 Number 1, June, 2022). The Journal covers general and Applied Microbiology, Biotechnology, Biological Sciences, Biochemistry, Bioinformatics, Medical, Public Health and Environmental sciences.

This year, UMYU Journal of Microbiology Research (UJMR) has reached its 5th year of publication which started in 2016. Over these years, many changes have been made to the typeface and general formats of the manuscripts, both the print version and online copies, to make the Journal meet the international standard and more visually appealing. From volume 3 (2) onward, all the online copies of UJMR papers on our website have been uploaded with their full colours. In addition, both authors and co-author are issued with e-certificates of publication for their respective published manuscripts.

We are glad that UJMR is gaining wider acceptance within Nigeria and in some foreign countries, and the number of submissions to the Journal is increasing. Despite the increase in manuscripts, UJMR maintained its quality as reflected by the rigorous peer-reviewing process. All articles submitted are accepted for publication based on a fair, objective, and anonymous assessment by our editors backed by the cogent decision by the editorial board. UJMR has thus increased the number of her associate editors by bringing in more people from academia who are experts in various fields within the scope of the Journal to enhance/maintain the speedy review of manuscripts received from various authors. The UJMR website has been upgraded so that UJMR readers and authors could get vital services such as online submission of manuscripts, downloading UJMR archives, author guidelines, etc.

UJMR’s vision is to be an internationally recognised premier journal of Microbiology, to contribute toward high-quality research and dissemination of UJMR to reach a larger audience worldwide. The journal is now indexed with reputable indexing organizations such as Crossref, Index Corpernicus International, International Institute of Organized Research (I2OR), Google Scholar, CiteSeerX, among others. In addition, the Journal has scored a publication impact factor of 2.525 for the year 2020 and Index Corpernicus value (ICV) of 85.02. Moreover, all our published articles are now assigned DOI. We hope that anyone with the expertise would join us and collaborate with our effort to obtain a much higher Impact Factor. We are delighted that UJMR is the first University-based microbiology journal in Nigeria. Therefore, we urge our academic colleagues to join hands with us towards projecting scientific research.

We appreciate the tireless efforts of the editorial board members, our editorial advisers, associate editors, and authors that contributed towards making UJMR a high-quality research journal. The support extended to the Journal by the Vice Chancellor and Umaru Musa Yar’adua University management is highly appreciated.

 

Dr. Bashir Abdulkadir

Editor – in – Chief       

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