Prevalence and Antibiotic Resistance Profiles of Methicillin-Resistant Staphylococcus aureus Isolated from Clinical Specimens in Anyigba, Nigeria

  • Mofolorunsho, K. C *, Emmanuel M. T, Omatola C.A, Aminu R. F. and Ocheni H. O.

  • UJMR 2022, 7(1), Pp 43 -51, DOI: 10.47430/ujmr.2271.007

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) is a major public health concern, and it is responsible for both hospital and community associated infections globally. In this study, we aimed at determining the prevalence and pattern of resistance of MRSA to commonly used antibiotics in Anyigba, Nigeria. This was a hospital based, cross-sectional study conducted between August 2017 and February 2018. One hundred and fifty routine clinical specimens were collected from selected health facilities in Anyigba for laboratory analyses. Standard laboratory methods were employed in the identification of the isolates. Methicillin-resistant Staphylococcus aureus (MRSA) was confirmed using Oxacillin Resistance Screening Agar Base (ORSAB) supplemented with 2g/l of Oxacillin. Screening to determine the antibiotic resistance profiles of all confirmed MRSA isolates was by disc diffusion method. A total of 124 (82.7%) isolates of Staphylococcus aureus were recovered from clinical samples obtained. Of these isolates, 28 (22.6%) were methicillin resistant. The percentage distribution rate of MRSA was highest (50.0%) in urine samples. Majority of these isolates were resistant to at least four of the six antibiotics tested. Most of the isolates recovered from urine samples were resistant to Gentamicin (92.9%), Amoxicillin (100.0%) and Cotrimoxazole (85.7%). Our study showed a significant presence of MRSA isolates in the clinical specimens collected, with a relatively high rate to gentamicin, Amoxicillin and Cotrimoxazole antibiotics. This study highlights the need for monitoring of antimicrobial use considering the lack of innovation in the development of new antimicrobials which lessens efforts at combating infections caused by antibiotic-resistant pathogens.

Keywords: Staphylococcus aureus, MRSA, Antibiotic resistance, Clinical specimens

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UJMR News

The Editorial Board of UJMR is glad to have published the Twelfth edition (Volume 7 Number 1, June, 2022). The Journal covers general and Applied Microbiology, Biotechnology, Biological Sciences, Biochemistry, Bioinformatics, Medical, Public Health and Environmental sciences.

This year, UMYU Journal of Microbiology Research (UJMR) has reached its 5th year of publication which started in 2016. Over these years, many changes have been made to the typeface and general formats of the manuscripts, both the print version and online copies, to make the Journal meet the international standard and more visually appealing. From volume 3 (2) onward, all the online copies of UJMR papers on our website have been uploaded with their full colours. In addition, both authors and co-author are issued with e-certificates of publication for their respective published manuscripts.

We are glad that UJMR is gaining wider acceptance within Nigeria and in some foreign countries, and the number of submissions to the Journal is increasing. Despite the increase in manuscripts, UJMR maintained its quality as reflected by the rigorous peer-reviewing process. All articles submitted are accepted for publication based on a fair, objective, and anonymous assessment by our editors backed by the cogent decision by the editorial board. UJMR has thus increased the number of her associate editors by bringing in more people from academia who are experts in various fields within the scope of the Journal to enhance/maintain the speedy review of manuscripts received from various authors. The UJMR website has been upgraded so that UJMR readers and authors could get vital services such as online submission of manuscripts, downloading UJMR archives, author guidelines, etc.

UJMR’s vision is to be an internationally recognised premier journal of Microbiology, to contribute toward high-quality research and dissemination of UJMR to reach a larger audience worldwide. The journal is now indexed with reputable indexing organizations such as Crossref, Index Corpernicus International, International Institute of Organized Research (I2OR), Google Scholar, CiteSeerX, among others. In addition, the Journal has scored a publication impact factor of 2.525 for the year 2020 and Index Corpernicus value (ICV) of 85.02. Moreover, all our published articles are now assigned DOI. We hope that anyone with the expertise would join us and collaborate with our effort to obtain a much higher Impact Factor. We are delighted that UJMR is the first University-based microbiology journal in Nigeria. Therefore, we urge our academic colleagues to join hands with us towards projecting scientific research.

We appreciate the tireless efforts of the editorial board members, our editorial advisers, associate editors, and authors that contributed towards making UJMR a high-quality research journal. The support extended to the Journal by the Vice Chancellor and Umaru Musa Yar’adua University management is highly appreciated.

 

Dr. Bashir Abdulkadir

Editor – in – Chief       

Abstracting and Indexing