Antibiotic sensitivity profile of Pseudomonas aeruginosa Isolated from abattoir in Ilorin Nigeria

Abstract

Background: Pseudomonas aeruginosa is frequently identified as the predominant bacterial pathogen in abattoir and aquaculture settings. In Kwara State, Nigeria, there has been a lack of thorough investigation into the impact of the organism on public health in the environment. Therefore, it was necessary to investigate the occurrence of P. aeruginosa and determine its resistance characteristics to antimicrobial agents in selected abattoir sites in Ilorin, Nigeria
Methodology: Wastewater samples were collected from randomly selected abattoirs (n = 36) various locations in Ilorin, Nigeria, into sterile universal bottles and transported to the microbiology laboratory at Kwara State University, Malete, for microbiological analysis. Pseudomonas aeruginosa was phenotypically confirmed on the culture plate by conventional morphological characteristics and biochemical tests. Antibiotic susceptibility testing of the P. aeruginosa isolates was performed by the disk diffusion test and results were interpreted using the Clinical and Laboratory Standards Institute (CLSI) zone diameter breakpoints. The multiple antibiotic resistance index (MARI) was calculated for each isolate.
Results: The prevalence of Pseudomonas aeruginosa was 94%, The antibiotic susceptibility result showed that P. aeruginosa exhibited a high resistance rate to cefotaxime (91.6.0%); amoxicillin-clavulanic acid (88.9%); cefuroxime (91.6%), ciprofloxacin 13.8%); meropenem (2.8%), erythromycin (11%) while 100% sensitivity was recorded against ofloxacin and gentamycin
Conclusion: The results of this study highlight the importance of close monitoring of abattoirs as they may serve as major sources for the environmental dissemination of antibiotic-resistant bacteria such as P. aeruginosa.