COMPARATIVE ANTI BACTERIAL EVALUATION OF TWO VARIETIES OF GINGER AGAINST SELECTED STRAIN OF BACTERIA

Abstract

COMPARATIVE ANTI BACTERIAL EVALUATION OF TWO VARIETIES OF GINGER AGAINST SELECTED STRAIN OF BACTERIA

¹Mohammed Sanni Aliyu,¹Aisha Aliyu Yunusa,²Abdulazeez Aminu Maulud,³Adamu Shehu Usman

Corresponding author: msaliyu69@gmail.com

ABSTRACT:

Ginger (Zingiber officinale) and its derivatives have been reported to display antibacterial activity which is connected to its ability to suppress bacterial biofilm formation. The present study was carried out to evaluate and contrast the antibacterial properties of the methanolic leaves and rhizome extracts of the local and improved varieties of Z. officinale against Staphylococcus aureus and Salmonella typhi. Prepared samples of Z. officinale were extracted with methanol using maceration method, and the extracts were used for antibacterial studies using Agar well diffusion technique. From the results, the methanolic leaf extract of local variety had MIC of 6.25mg/ml and MBC of 12.5mg/ml, while the improved variety had MIC of 25.0mg/ml and MBC of 50.0mg/ml against Staphylococcus aureus. Local variety had MIC of 1.56mg/ml and MBC of 3.13mg/ml, while the improved variety had MIC of 25.5mg/ml and MBC of 50.0mg/ml against Salmonella typhi. Methanolic rhizome extract of local variety had MIC 25.05mg/ml and MBC of 50.05mg/ml, while improved variety had MIC of 25.05mg/ml and MBC of 50.05mg/ml against Staphylococcus aureus. Local variety had MIC of 12.55mg/ml and MBC of 25.05mg/ml, while improved variety had MIC of 12.55mg/ml and MBC of 25.05mg/ml against Salmonella typhi. Findings from antibacterial screening indicates that methanolic extracts of both varieties had significant and concentration dependent antibacterial activity against the bacterial strain tested.

Keywords: Zingiber officinale, Antibacterial, Staphylococcus aureus and Salmonella typhi