Prevalence of HEV among pregnant women attending selected Antenatal clinics in Kano Metropolis

HEV in pregnancy

Abstract

Hepatitis E Virus (HEV) is the leading cause of acute viral hepatitis worldwide, particularly in immunocompromised individuals. The study investigated the prevalence of HEV infection in pregnant women attending antenatal clinics In Kano Metropolis. One hundred and twenty-three (123) subjects were enrolled for the study and their sera was analyzed for HEV antigen using Enzyme Linked Immunosorbent Assay (ELISA). The results showed that 9 (7.3%) subjects tested positive for HEV. The study found that HEV infection was more common among women aged 20-24 (6, 66.7%), those with secondary school education (8, 88.9%), and entrepreneurs (4, 44.4%). Additionally, women who had occasional contact with animals (5, 55.6%), received blood transfusions (9, 100%), and used borehole water (8, 88.9%) were more likely to be infected. Statistical analysis revealed a significant relationship between HEV infection and contact with animals (P<0.05). The study highlights the need for public awareness and education to prevent the spread of HEV infection among pregnant women in Kano Metropolis.