Antimicrobial activity of Balsam Apple (Mormodica balsamina L.)

Authors

  • Abubakar Bello Center for Biodiversity and Conservation, Department of Biology, Faculty of Natural and Applied Sciences, Umaru Musa Yar’adua University, P.M.B 2218, Katsina, Nigeria.
  • Fatima Muhammad Center for Biodiversity and Conservation, Department of Biology, Faculty of Natural and Applied Sciences, Umaru Musa Yar’adua University, P.M.B 2218, Katsina, Nigeria.
  • Sulaiman S. Kankara Center for Biodiversity and Conservation, Department of Biology,Faculty of Natural and Applied Sciences Umaru Musa Yar’adua University, P.M.B 2218, Katsina, Nigeria.
  • Bashir Abdulkadir Microbiology, Faculty of Natural and Applied Sciences, Umaru Musa Yar’adua University, P.M.B 2218, Katsina, Nigeria.
  • Buhari Y. Shinkafi Center for Biodiversity and Conservation, Department of BiologyFaculty of Natural and Applied Sciences, Umaru Musa Yar’adua University, P.M.B 2218, Katsina, Nigeria.

DOI:

https://doi.org/10.47430/ujmr.1831.004

Abstract

Momordica balsamina L. commonly known as African pumpkin or Balsam apple (Cucurbitaceae) is used as vegetable in many African countries and traditionally in the treatment of skin diseases. In this study, phytochemical prospective and antimicrobial activities of its leaf extracts were evaluated with the view to validating its medicinal potentials. Acetone, ethanol and water were used as the extracting solvents. Presence of various secondary metabolites as tannins, flavonoids, proanthocyanidins, alkaloids and saponins were observed. Acetone extract indicated a significant inhibition in all the bacterial isolate (Escherichia coli, Staphylococcus aureus, and Salmonella typhi) tested at 100 mg/ml (P<0.05) followed by ethanol extract which inhibited the growth of E. coli and S. aureus. The water extract showed a significant (P<0.05) inhibition on the growth of E. coli and Sa. typhi. The result of antifungal assay showed that acetone extract suppressed the growth of Aspergillus niger and Rhizopus sp at 100 mg/ml. The results obtained provided a scientific support for the claimed ethnomedicinal uses of the leaves of M. balsamina and suggested its potential as a source of a lead compound in the treatment of microbial infections. Key words: Acetone, Bacteria, ethnobotany, Fungi, Methanol, water

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References

Alade, P.I. and Irobi, O.N. (1993). Antimicrobial Activities of Crude leaf extract of Acalypha wikensiana. J. ethnopharmacol 39:71-174.

https://doi.org/10.1016/0378-8741(93)90033-2

Aliero, A.A. and Wara, S.H. (2009). Validating the Medicinal Potential of Laptadenia hastata. African Journal of Pharmacy and Pharmacology. 3(6): 335-338

Bello A., Aliero A.A., Saidu Y., Muhammad S. (2011a). Evaluation of Polyphenolic Content and Alpha-Glucosidase Inhibitory Effect of Leptadenia hastata (Pers.) Decne. Nigerian Journal of Botany, 24 (2): 331-339.

Bello A., Aliero A.A., Saidu Y., Muhammad S. (2011b). Hypoglycaemic and Hypolipidaemic Effects of Leptadenia hastata (Pers.) Decne in Alloxan Induced Diabetic Rats. Nigerian Journal of Basic and Applied Science, 19 (2): 187−192.

Burkill, H. M. (1994). The useful plants of west tropical Africa. Volume 2: Families EI (No. Edn 2). Royal Botanic Gardens.

Bax, R, and Mullan, V. (2000). The Millennium bugs 'the need for and development of new Antibacterials' Interm. J Antimicrob Agent., 16:51-59

https://doi.org/10.1016/S0924-8579(00)00189-8

Cohen, M.L. (1992). Epidemiology of drug resistance 'Implications for a Post Antimicrobial Era. Science 257:1050- 1055.

https://doi.org/10.1126/science.257.5073.1050

Duraipandiyan, V., Muniappan, A., and Ignacimuthu, S. (2006). Antimicrobial activity of some ethnomedicinal plants used by Paliyar tribe from Tamil Nadu, India. BMC Complimentary and Alternative Medicine. 6: 35

https://doi.org/10.1186/1472-6882-6-35

Edeoga, H. O., Okwu, D. E., & Mbaebie, B. O. (2005). Phytochemical constituents of some Nigerian medicinal plants. African journal of biotechnology, 4(7), 685-688.

https://doi.org/10.5897/AJB2005.000-3127

El-Olemy, M.M, Farid, J.A. and Abdel-fattah, (1994). Experimental Phytochemistry. A laboratory manual. College of Pharmacy, King said University; Riyadh p 3-61

Gill LS (1992). Ethnomedicinal uses of plants in Nigeria. University of Benin press, Benin, Nigeria, p. 223. Hassan, L.G. and Umar, K.J (2006). Nutritional Value of Balsam Apple (Momordica balsamina L.) Leaves. Pakistan Journal of Nutrition. 5 (6): 522-529.

https://doi.org/10.3923/pjn.2006.522.529

Jagessar, R.C., Mohammed, A. and Gomes, G. (2008). An Evaluation of the Antibacterial and Antifungal activity of leaf extracts of Momodica charantia against Candida albicans,Staphylocous aureus, and Escherichia coli. Nature and science, 6 (1): 1-4.

John, K. J., & Antony, V. T. (2010). A taxonomic revision of the genus Momordica L.(Cucurbitaceae) in India. Indian Journal of Plant Genetic Resources, 23(2), 172-184.

Jose Galberto, M. Eidla, M.M., Adriana, R.C. and Fabiola, F.G., (2011). Antibacterial activity of Momordica charantia (Curcubitaceae) Extracts and fractions. Journal of basic and Clinical pharmacy 002 (1): 45-51.

Kandaswami C.E., Perskins D.S., Solonink G, Arzewiecki, Middle E. (1994). Anti- preventive effects of citrus flavonoids on human squamous cell carcinoma in vitro. Cancer lett 56: 147-157.

https://doi.org/10.1016/0304-3835(91)90089-Z

Murray, P.R, Baron, E.J, Ptalber, M.A., Terrover, F.C. and Yolke, R.H. (1995). Manual of clinical Microbiology 6th ed. Mosty year Book London.

Nascimento, G.F, Juliana, L., Paulo, C.F. and Givliana, L.S. (2000). Antibacterial activity of plant extract and phytochemicals on antibiotic resistant bacteria. Braz. J. Microbial., 31: 247-256

https://doi.org/10.1590/S1517-83822000000400003

Okwu, D. E. and Okwu, M. E. (2004). Chemical composition of Spondias mombin Linn. Plants parts. Journal of Sustainable Agriculture and Environment, 6(2): 140-147.

Sunday, O.O., Uguru, M.O. and Ogbonna A. (2008). Antimicrobial and hypoglycemic Effects of Momordica balsamina. Linn. Journal of natural products. 1:3-9

Trease, G.E. and Evans, W.C. (1985). Pharmacognosy, 12th edition, English language Books Society, Bailliere Tindall. P.394

UNESCO, (1996). Culture and health, Orientation Texts, World Decade for Cultural Development 1988-1997. Document CLT/ DEC/PRO - 1996, Paris, France. P. 129.

Vadhana, P., Singh, B. R., Bharadwaj, M., & Singh, S. V. (2015). Emergence of herbal antimicrobial drug resistance in clinical bacterial isolates. Pharm Anal Acta, 6(10), 434.

https://doi.org/10.4172/2153-2435.1000434

Welman, M. (2004). Momordica balsamina L. Nutritional Herbarium, Pretoria. www.plantzafrica.com/platk/m/momo rdbalsam.htm. Retrieve on 17/05/2005

WHO (2001). Legal status of traditional Medicine and Complementary Alternative medicine A World wide review. WHO Publishing 1

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Published

30-06-2018

How to Cite

Abubakar Bello, Fatima Muhammad, Sulaiman S. Kankara, Bashir Abdulkadir, & Buhari Y. Shinkafi. (2018). Antimicrobial activity of Balsam Apple (Mormodica balsamina L.). UMYU Journal of Microbiology Research (UJMR), 3(1), 24–29. https://doi.org/10.47430/ujmr.1831.004