STREPTOCOCCUS MUTANS CAUSING TOOTH DECAY FROM PATIENTS ATTENDING MURTALA MUHAMMED SPECIALIST HOSPITAL, KANO STATE NIGERIA
Keywords:
Antibiotics, Dental caries, Linezolid, Streptococcus mutans, Tooth decayAbstract
Globally, it is estimated that 2 billion people suffer from caries of permanent teeth and 520 million children suffer from caries of primary teeth. Bacteria such as Streptococcus mutans, and Lactobacilli are among the most common pathogens that mostly cause tooth decay. There are an estimated more than 1.5 million cases of tooth decay reported in Nigeria yearly, which occur in all individuals at apparently no age preferences. Tooth decay normally results in serious pain, infections, and loss of teeth if not properly treated. The present study aims to determine the presence of Streptococcus mutans causing tooth plaque from patients attending Murtala Muhammed Specialist Hospital, Kano State Nigeria. A total of 400 samples of oral dental plaque were collected and processed using standard microbiological procedure; include culture, Gram stain, catalase test, optochin susceptibility screening test and confirmed to the species level by Analytical Profile Index 20 Strep (API 20 Strep). Confirmed, S. mutan were subjected to antimicrobial susceptibility test against some common antibiotics. Of 400 samples enrolled 87.8% (351/400) shows positive bacterial growth and 87 was confirmed to be S. mutan. Great antimicrobial activity was observed to linezolid, clindamycin and ciprofloxacin against the isolated S. mutan.
Downloads
References
Abo Bakr R., Tawfick M., Mostafa Z., Abdulall A. (2022). Prevalence and Antibiogram of Streptococcus mutans in Dental Plaque and Caries Samples. Azhar International Journal of Pharmaceutical and Medical Sciences. 2022; 2 (2): 83-93,
Alhasani AH, Ishag RA, Yahya Al-Akwa AAY, Al Shamahy HA, Al-labani MA. Association between the Streptococcus mutans biofilm formation and dental caries experience and antibiotics resistance in adult females. Universal J Pharm Res 2020; 5(6):1-3.
Alhasani AH, Ishag RA, Yahya Al-Akwa AAY, Al Shamahy HA, Al-labani MA. Association between the Streptococcus mutans biofilm formation and dental caries experience and antibiotics resistance in adult females. Universal J Pharm Res 2020; 5(6):1-3.
Alsamhari MMA, Al-Najhi MMA, Al-Shamahy HA, Al-dossary OAI. Analysis of biofilms for streptococcus mutans from dental root surfaces of adult patients with root caries. Universal Journal of Pharmaceutical Research 2021; 6(5):19-23.
Al-Shami IZ, Al-Shamahy HA, Abdul Majeed ALA, Al- Ghaffari KM, Obeyah AA. Association between the salivary Streptococcus mutans levels and dental caries experience in adult females. On J Dent Oral Health 2018; 1(1):1-6.
Centre for Disease Control and prevention (2014). Laboratory Methods for the Diagnosis of Meningitis Caused by Neisseria meningitidis, Streptococcus pneumoniae and Haemophilus influenzae, 2nd Edition.
Cheesbrough, M. (2010). District Laboratory Practice in Tropical Countries. Cambridge university press, 2:132-142, 382-416.
Cheesebrough, M., (2006). District Laboratory Practice in Tropical Countries Part 2, Cambridge. University Press, Cambridge. P. 47-54.
Gao, Y., Shang, Q., Li, W., Guo, W., Stojadinovic, A., Mannion, C. and Chen, T. (2020). Antibiotics for cancer treatment: A double-edged sword. Journal of Cancer, 11(17), 5135.
Henza SL, Damé-Teixeirab N, Portugalc CN, Maltza M. Bacterial analysis of biofilms from tooth root surfaces presenting different caries activity. Revista da Faculdade de Odontologia de Porto Alegre 2020; 61(1):1-6.
Laudenbach, J. M and Simon, Z (2014). Common Dental and Periodontal Diseases: Evaluation and Management. The Medical clinics of North America. 98 (6): pp 1239- 1260
Marsh, P. D., Head D.A. and Devine D.A. (2015). Dental plaque as a Biofilm and a Microbial Community-Implications for treatment. Journal of Oral Biosciences. 57 (4): pp 185–191.
Matsumoto-Nakano M. Role of Streptococcus mutans surface proteins for biofilm formation. Japanese Dental Science Review. 2018;54(1):22-29.
National Bureau of Statistics (NBS) (2018).The latest population figures from National Bureau of Statistics you need to see; Business Insider by Pulse; Retrieved on 15th June 2022.
Patterson, M. J. (1996). ‘Streptococcus’. Baron’s Medical Microbiology. 4th Edition. University of Taxas Medical Branch. ISBN-0-9631172-1-1.
Salh, A., Risan, M., & Jasim, H. (2022). Biochemical Characteristics and Antibiotics Susceptibility of Streptococcus Mutans Isolates from Dental Caries in Baghdad City. International Journal of Advanced Biological and Biomedical Research, 10(1), 32-43.
Sanda, M. I. and Idris, A. M. (2021). Nasopharyngeal Carriage of Staphylococcus aureus among Horses and Horse Handlers in Kano Metropolis, Nigeria. Umar Musa Yar’adua University Journal of Microbiology Research. 6(1):1 – 10.
Tripathi, N. and Sapra, A. (2021). Gram Staining; StatPearls Publishing: Treasure Island, FL, USA, 2021.
Uddin, T. M., Chakraborty, A. J., Khusro, A., Zidan, B. R. M., Mitra, S., Emran, T. B., ... & Koirala, N. (2021). Antibiotic resistance in microbes: History, mechanisms, therapeutic strategies and future prospects. Journal of infection and public health, 14(12), 1750-1766.
Wong, A., Paul, E.S, Douglas A.Y. Journal of Advances in Pediatrics 64 (2017). Advance in Pediatrics 307-330
Yahaya, S. and Ramatu, A. M. (2017). Prevalence of Pathogenic Microorganisms in the Oral Cavity and Their Sensitivity to Some Selected Dentifrice Sold At Major Markets In Kano Metropolis. Bayero Journal of Pure and Applied Sciences, 10(1): 227 – 233.
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Abdulrazak Muhammad IDRIS
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
