Comparative Study on Antifungal Effects of Calotropis procera and Ficus gnaphalocarpa Latex against Tinea capitis
DOI:
https://doi.org/10.47430/ujmr.1831.006Keywords:
Calotropis procera, Ficus gnaphalocarpa, Epidermophyton floccosum, Trichophyton rubrum, Microsporum canisAbstract
This study was conducted to evaluate and compare the antifungal activities of Calotropis procera and Ficus gnaphalocarpa latex against three scalp ring worms; Epidermophyton floccosum, Trichophyton rubrum and Microsporum canis using agar well diffusion method at
1.3 and 1.4ml latex concentrations. The plants latex was obtained at Rafin Guzuma and Giwa tazo village’s farms at Maiyama Local Government Area of Kebbi State. Scalp ringworm samples were collected from pupils in (5) five Model Primary Schools within the study Area namely: Muhammadu Bello Dunbegu, Giwa tazo, Rafin Guzuma, Gidiga and Saran dosa Model Primary Schools. The antifungal assay results portrayed broad spectrum activity against the three dematophytes: Epidermophyton floccosum, Trichophyton rubrum and Microsporum canis tested with comparable inhibitory zones ranged from 13.28 to 16.10mm for C. procera latex and 14.09 to 18.10mm for F. gnaphalocarpa latex as compared with the positive control (Griseofulvin). The study conducted revealed that, F. gnaphalocarpa latex has higher antifungal effect compared to C. procera latex on the test organisms.
Downloads
References
Ajoku, G.A., Ibrahim, K., Ewerem, N.M., Odama, L.E. and Iyang, U.S. (2005). Preliminary screening of Datarium senegalensis against some isolates of type culture collection (ATCC). Nigerian Journal of Botany, 18:289- 293.
Aliero, B.L., Umar M.A., Suberu, H.A., and Abubakar, A.A. (2001). Handbook of Common Plants in North Western Nigeria. 1st edition Sokoto. Usmanu Danfodiyo University Press, pp. 40-48.
Berg, C.C. (1999). Annotated check-list of the Ficus species of the African floristic region, with special reference and a key to the taxa of Southern Africa. Kirkia,13:253-291.
Binder, B., Richtig, E., and Weger, W. (2009). Tinea capitis in early infancy treated with itraconazole: a pilot study. JEADV, 23:1161-1163.
https://doi.org/10.1111/j.1468-3083.2009.03271.x
Campbell, C.K., Johnson, E.M, Philpot, C.M. and Warnock, D.W. (1999). The dermatophytes. In: Identification of pathogenic fungi. London: PHLS, pp. 26-68.
Cheesbrough, M. (2006). District Laboratory Practice in Tropical Countries. 2nd ed. Cambridge, New York: Cambridge University Press.Pp 298-314
https://doi.org/10.1017/CBO9780511543470
Chevalier, A. (2001). A encyclopedia of medical plants. London: Dorling Kindersley publication, The University of Michigan. Chitme, H.R., Chandra, R. and Kaushik, S. (2003). Journal of pharmaceuticalsciences, 7:70-75
Elewski, B.E. (2008). Tinea capitis: a current perspective. Journal of American Acadamy of Dermatology, 42:1-20.
https://doi.org/10.1016/S0190-9622(00)90001-X
Galal, A.A., Azzeddine, K., Khadija, K., Laila, O., Mahjouba, M., Reda, C. and Zakaria, M. (2012). " In vitro antimicrobial activity of aqueous and ethanolic extracts of leaves of Ficus craica collected from five different regions of Morocco." Journal of Material Environmental Science 4(1): 33-38.
Ghani, A. (2003). Medicinal Plants of Bangladesh with chemical constituents and uses Asiatic Society of Bangladesh, Nimtali, Dhaka.pp. 42-48.
Goyal, D., Sharma, S. and Mahmood, A. (2013). Inhibition of dextransucrase activity in Streptococcus mutans by plant phenolics. Indian Journal of Biochem Biophys, 50:48- 53
Goyal, M. and Mathur, R. (2011). Antimicrobial potential and phytochemical analysis of plant extracts of Calotropis procera. International Journal of Drug Discovery and Herbal Research, 1(3):138-143.
Halder, R.M., Robert, C.I., Nootheti, P.K. and Kelly, A.P. (2006). Dermatologic Disease in blacks. Dermatology and dermatological therapy of pigmented skin, Pp. 331-355.
https://doi.org/10.3109/9780203485699
Halua, B. and Vidyasagar, G. (2012). A comparative study differential antimycoses activity of crude leaf extract of Calotropis species. International Journal of Pharmacological Science, 4 (3): 705-708.
Iqbal, Z., Lateef, M., Jabbar, A., Muhammad, G. and Khan, M.N. (2015). Anthelmintic activity of Calotropis procera (Ait.) Ait. F. flowers in sheep. Journal of Ethnopharmacology, 102(2):256-261.
https://doi.org/10.1016/j.jep.2005.06.022
Kareem S.O., Akpan, J. and Oja, O.P (2008). Antimicrobial activities of C. procera on selected pathogenic microorganisms. African Journal of Biomedical Research, 11: 105-110.
https://doi.org/10.4314/ajbr.v11i1.50674
Kuete, V., Kamga, J., Sandjo, L.P., Ngameni, B., Poumale, H.M.P., Ambassa, P. and Ngadjui, B.T. (2011). Antimicrobial activities of the methanol extract, fractions and compounds from Ficus polita Vahl. (Moraceae). BMC Journal Complementary and Alternative Medicine, 11:6.
https://doi.org/10.1186/1472-6882-11-6
Kuta, F.A. (2008). Antifungal effect of Calotropis procera stems bark on E.Floccosum and T. gypseum. African Journal of Biotechnology, 7(13): 2116-2118.
Mann, A., Yahaya, V., Banso, A. and John, F. (2008). Journal of medicinal plants research, 2:094-097.
Mbakwem-aniebo, C., Onianwa, O. and Okonko, O. (2012). Effects of Ficus expert Vahl on common Dermatophytes and causative agent of Pityriasis versicolor in Rivernstate, Nigeria. American Journal of Dermatology and Venerology, 1(1):1-5.
Michel, A. (2004). Tree, Shrub and Linas of West African dry zones. Grad Margraf Publishers, pp. 399-405.
Mohrenschlager, M., Seidl, H.P. and Ring, J. (2005). Pediatric Tinea capitis: recognition and management. America Journal Clinical Dermatology, 6(4):203- 213.
https://doi.org/10.2165/00128071-200506040-00001
Mossa, J.S., Tariq, M., Mohsin, A., Ageel, A.M., Al- Yahya, M.A. and al-Said, M.S. (1991). Pharmacological studies on aerial parts of Calotropis procera. American Journal China Medicine, 19:223-31.
https://doi.org/10.1142/S0192415X91000302
Mukherjee, B., Bose, S. and Dutta, S.K. (2010). Phytochemical and pharmacology investigation of fresh flower extract of Calotropis procera Linn. International Journal of Pharmaceutical Sciences and Research, 1(2):182-187
National Population Commission (NPC). (2006).Census Report. Abuja, Nigeria.
Rabiu, M.A., Mikaeel, B.A., Adamu, B.K., Yakubu, Y.D., Nafiu, L., Mohammad, B.B. and Aminu, Y.F. (2015). Efficacy and phytochemical analysis of latex of Calotropis procera against selected dermatophytes. Article from Journal of Intercultural Ethnopharmacology, 4(4):314-317.
https://doi.org/10.5455/jice.20151012012909
Saadabi, M.A., Patrick, A.O. and Gregory, A.C. (2012). Phytochemical screening and effect of aqueous extract of Ficus syccomorus L. (Moraceae) stem bark on muscular activity in labarotory animals. Journal of Ethnopharmacology, 103:481- 483.
https://doi.org/10.1016/j.jep.2005.08.025
Shinwari, M.I. and Khan, M.A. (2000). Folk use of medicine herbs of Margalla hills national park, Islamabad. Journal of Ethnopharm, 69:45-56
https://doi.org/10.1016/S0378-8741(99)00135-X
Talaro, P.K. (2005). Foundation in microbiology, fourth edition. McGraw hill New York, pp. 678-679
Thakur, R. (2013). Tinea capitis in Botswana: Clin cosmet investing Dermatol, 5:37-41. Umar, M.A. and Azare, B.A. (2006). Nutrient contents of some selected feeds. Biology and Environmental Science Journal of Tropics, 3: 110-113.
https://doi.org/10.2147/CCID.S40053
Umar, M.A. and Azare, B.A. (2006). Nutrient contents of some selected feeds. Biology and Environmental Science Journal of the Tropics, 3: 110-113.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 UMYU Journal of Microbiology Research (UJMR)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
