Seroprevalence and Risk Factors Associated with Hepatitis B Virus Infection among Pregnant Women Attending Antenatal Care in Azare, Bauchi State, Nigeria
DOI:
https://doi.org/10.47430/ujmr.2051.002Keywords:
Seroprevalence,, Hepatitis B virus,, pregnant women,, Rapid Test StripAbstract
Hepatitis B virus is known to thrive in peripheral mononuclear cells, tissues of pancreas, spleen, kidney, skin, fluids such as saliva, semen, sweat, breast milk, tears, urine as well as vaginal secretion. This study was carried out to determine the seroprevalence of Hepatitis B virus infection and associated risk factors among pregnant women attending antenatal care in General Hospital Azare, Bauchi State. In this study, 100 consenting pregnant women were recruited and their blood samples were screened for HBs Ag using Rapid Test Strip. A structured questionnaire was used to obtain information about the socio-demographic and risk factors of the study population. Data obtained were subjected to Chi-square test using statistical package for social science (SPSS) version 20 to determine the association between risk factors and Hepatitis B virus infection. The result showed that the overall seroprevalence of Hepatitis B virus infection among pregnant women attending General Hospital, Azare, was 6(6.0%). Highest seroprevalence of HBsAg (16.7%) was observed among pregnant women within the age group of 36-40 years so also unemployed pregnant women (6.8%) had the highest seroprevalence of HBs Ag. Previous history of blood transfusion, previous history surgery, use of contraceptives, sharing of sharp objects and sharing of tooth brush were found to be the risk factors associated with pregnant women in Azare. The differences observed in the seroprevalence of HBs Ag with different demographic and risk factors were not significant (P>0.005), with the exception of age (p = 0.03). Pregnant women and the general public should be enlightened on the risk factors associated with hepatitis B virus infection.
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References
Agarry, O.O. andLekwot, G.Z. (2010). Prevalence of hepatitis B virus and hepatitis C virus in ante-natal patients in Gwagwalada- Abuja, Nigeria, Science pub, 2(7):48-50.http://www.sciencepub.net/report Ahmedin, J., Taylor, M., Ram, C.T., Asma, G.,
Alicia, S., Elizabeth, W.; Eric J.F., Michael, J.T. (2004). A New Section in Cancer Offering Timely and Targeted information, A Cancer Journalfor Clinicians. 54 (8):48-50.
Alberstein, M., Zornitzki, T., Zick, Y. andKnobler, H. (2012). Hepatitis C care protein in pairsinsulin down stream signaling and regulatory role of IGFBP. Journal of viral Hepatitis, 19:65-71.
https://doi.org/10.1111/j.1365-2893.2011.01447.x
Bankole, H.O., Richard, O. and Oladapo, B.O. (2013). Prevalence of HIV, HBV, And HCV infections among pregnant women receiving antenatal care in a traditional birth home in Benin City, Nigeria. Saudi Journal for Health Sciences, 2(20): 113-117.
https://doi.org/10.4103/2278-0521.117916
Chang, M.H.(2008). Hepatitis B virus infection.Foetal, Neonatal Medicine, 12:160-1672
https://doi.org/10.1016/j.siny.2007.01.013
Chen, C.T. (2014).A brief history of hepatitis milestones. Liver International. 34(1):20-37.
https://doi.org/10.1111/liv.12409
Dessie, T., Kassu, D., Belete, T. and Tesfaye, T. (2014). Seroprevalence and transmission of Hepatitis B virus among delivering women and their new born in selected health facilities, Addis Ababa, Ethiopia: a cross sectional study. Biomedical Research Notes,7: 239.
https://doi.org/10.1186/1756-0500-7-239
Elinav, E., Ben-Dov, I.Z., Shapira, Y., Daudi, N., Adler, R., Shouval, D. and Ackerman Z. (2006). Acute hepatitis A infection in pregnancy is associated with high rates of gestational complications l and preterm labor. Gastroenterology, 130: 1129-1134.
https://doi.org/10.1053/j.gastro.2006.01.007
Esan, A.J, Omisakin, C.T., Ojo-Bola, T.,Owoseni, M.F., Fasakin, K.A. and Ogunleyea, A. (2014). Sero-Prevalence of Hepatitis B and Hepatitis C Virus Co- Infection among Pregnant Women in Nigeria. American Journal of Biomedical Research, 2(1): 1-15.
https://doi.org/10.12691/ajbr-2-1-3
Ge, D., Fellay, J., Thompson, A.J., Simon, J.S., Shianna, K.V., Urban, T.J., Heinzen, E.L., Qiu, P., Bertelsen, A.H., Muir, A.J., Sulkowski, M., McHutchison, J.G. and Goldstein, D.B. (2009). Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance. Nature, 461(7262):399-401
https://doi.org/10.1038/nature08309
Habtie, T., Belete, B., Fasika, G., Kifle, T., Gizachew, Y. andDagnachew, M. (2013). Seroprevalence of hepatitis B and C virus infection among patients attending serology laboratory of Gondar University Hospital. Biomedical Research Notes, 6: 164.
https://doi.org/10.1186/1756-0500-6-164
Isa, I., Amonu, M. Abdullahi, S.A., Sani, M.A. and Eson, M.D. (2015). Seroprevalence of Hepatitis B Virus in a Tertiary Institution in North Western Nigeria. African Journal of Microbiology Research, 9(3):171-179.
https://doi.org/10.5897/AJMR2014.7068
Jibrin, Y.B., Kolo, P.M., Mohammed, A., Sanya,E.O. andAliyu, L.D. (2016). Burden of hepatitis B and C infections among pregnant women in Bauchi, NortheasternNigeria. Sub-Saharan African Journal of Medicine, 3:188-93.
https://doi.org/10.4103/2384-5147.210204
Jinli, D. and Hongjun, L., (2015).Literature analysis of radiological studies on viral hepatitis. Radiology of Infectious Diseases, 2(2):57-60
https://doi.org/10.1016/j.jrid.2015.10.001
Mustapha, G.U., Ibrahim, A., Balogun, M.S., Umeokonkwo, C.D. and Mamman, A.I. (2020). Seroprevalence of hepatitis B virus amongantenatal clinic attendees in Gamawa LocalGovernment Area, Bauchi State, Nigeria. BMC Infectious Diseases, 20(194):1-6.
https://doi.org/10.1186/s12879-020-4863-9
Oluboyo, B.O., Ugochukwu, V.I., Oluboyo, A.O., Ihim, A.C., Chukwuma, G.O., Ogenyi, S.I., and Onyemelukwe, A. (2014). Prevalence of Hepatitis B and C Viral Infections In Pregnant Women Attending Antenatal Clinic In Nnewi Nigeria. European Scientific Journal, 10(3):1857 -7881.
Pennap, G.R., Yakubu, A., Oyige, O., Forbi, J(2010). Prevalence of hepatitis B and C virus infection among people of a local community in Keffi, Nigeria. African Journal of Microbiology Research.4(4):274-278.
Pungpapong, S., Kim, W.R. and Poterucha J.J. (2007). Natural History of Hepatitis B Virus Infection: An Update for Clinicians. Mayo Clinical Procedures,82: 967- 975.
https://doi.org/10.4065/82.8.967
Richard, E., Isaac, A., Samuel, A.S., Joyce, A. and Hope A. (2015). Seroprevalence and risk factors of Hepaitis B and Hepatitis C infection among pregnant women in the Asente North Municipality of the Ashanti region Ghana; a cross sectional study. African health sciences, 15(3): 709-713.
https://doi.org/10.4314/ahs.v15i3.2
Sabria, R., Charles, K. and Said, A. (2014). Seroprevalence of hepatitis B virus infection among antenatal clinic attendees at a tertiary hospital in Dares Salaam, Tanzania. Tanzania Journal of Health Research, 16(1): 1-8
https://doi.org/10.4314/thrb.v16i1.2
Ugbebor, O., Aigbirior, M., Osazuwa, F., Enabudosoe, and Zabayo, O. (2011). The prevalence of hepatitis B and C viral infections among pregnant women. North American Journal of Medical Sciences, 3(5):238-241.
https://doi.org/10.4297/najms.2011.3238
World Health Organization (2010). Prevalence of hepatitis B virus in the world by country.
Yakasai, I.A., Ayyuba, R., Abubakar, I.S. and Ibrahim, S.A. (2012). Sero-prevalence of Hepatitis B Virus Infection and its Risk factors amongPregnant Women Attending Antenatal Clinic at Aminu Kano TeachingHospital, Kano, Nigeria. Journal of Basic and Clinical Reproductive Sciences, 1(1-2):49-55
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