Antibiogram of Candida Species using Different Susceptibility Testing Techniques: A Systematic Review

Authors

  • Sule, H. Department of Medical laboratory Science, Faculty of Allied Health Sciences, College of Health Sciences, Bayero University, Kano
  • Kumurya, A. S. Department of Medical laboratory Science, Faculty of Allied Health Sciences, College of Health Sciences, Bayero University, Kano
  • Ibrahim, A. Department of Medical laboratory Science, Faculty of Allied Health Sciences, College of Health Sciences, Bayero University, Kano

DOI:

https://doi.org/10.47430/ujmr.2051.006

Keywords:

Susceptibility,, Candida species,, Antifungal agents,, testing techniques

Abstract

Susceptibility pattern determination is a valuable key towards successful treatment of infectious diseases. Susceptibility of Candida species to different antifungal agents are also a common practice, however, different methods are employed to achieve the same goal. Some of the different techniques include: Disc diffusion method, Epsilometre test (E-test), Candfast, Microdilution technique among others. Fluconazole, Voriconazole, Itraconazole and Amphotericin B are some of the antifungal agents commonly used for treatment of infections due to Candida species. Most of these antifungals are also covered in this review. The commonly encountered Candida species in clinical settings include: C. parapsilosis, C. tropicalis, C. albicans, C. krusei, and C. glabrata. This review also gave some insight into their variable susceptibility pattern, as it affects different methods of susceptibility testing. There were reports of resistance from researchers from different regions across the globe; this therefore, signifies the importance of availability of data with regards to susceptibility of these species.

 

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References

Abi-Said, D., Anaissie, E. Uzun, O. Raad, I. Pinzcowski, H. and Vartivarian. S. (1997). The epidemiology of hematogenous candidiasis caused by different Candida species. Clin. Infect. Dis. 24:1122-1128. Erratum, Clinical Infectious Disease 25:352

https://doi.org/10.1086/513663

Aher, C. S. (2014). Species distribution, virulence factors and antifungal susceptibility profile of Candida isolated from oropharyngeal lesions of HIV infected patients. Int. J. Curr. Microbiol. App. Sci; 3(1):453446.

Arendrup, M. C., Dzajic, E., Jensen, R. H., Johansen, H. K., Kjaeldgaard, P., Knudsen, J. D., Kristensen, L., Leitz, C., Lemming, L. E. & other authors (2013). Epidemiological changes with potential implication for antifungal prescription recommendations for fungaemia: data from a nationwide fungaemia surveillance programme. Clinical Microbiol and Infectious disease 19:E343-E353.

https://doi.org/10.1111/1469-0691.12212

Arikan, S, Gur, D. Akova, M.(1997) Comparison of Etest, microdilution and colorimetric dilution with reference broth macrodilution method for antifungal susceptibility testing of clinically significant Candida species isolated from immunocompromised patients. Mycoses; 40: 291-296

https://doi.org/10.1111/j.1439-0507.1997.tb00234.x

Becerra, M. R., Tantalea' n, J. A., Sua' rez, V. J., Alvarado, M. C., Candela, J. L. & Urcia, F. C. (2010). Epidemiologic surveillance of nosocomial infections in a Pediatric Intensive Care Unit of a developing country. BMC Pediatr 10:66- 74.

https://doi.org/10.1186/1471-2431-10-66

Cleveland, A. A., Farley, M. M., Harrison, L. H., Stein, B., Hollick, R., Lockhart, S. R., Magill, S. S., Derado, G., Park, B. J. & Chiller, T. M. (2012). Changes in incidence and antifungal drug resistance in candidemia: results from population-based laboratory surveillance in Atlanta and Baltimore, 2008-2011. Clin Infect Dis 55:1352-1361.

https://doi.org/10.1093/cid/cis697

Clinical and Laboratory Standards Institute (2009). Method for antifungal disk diffusion susceptibility testing of yeasts, 2nd ed. CLSI document M44, Clinical and Laboratory Standards Institute, Wayne, PA.

Clinical and Laboratory Standards Institute (2017). Reference method for broth dilution antifungal susceptibility te sting of yeasts; Approved standard, 4th ed, CLSI document M27, Clinical and Laboratory Standards Instit ute, Wayne, PA.

Cuenca-Estrella, M. Lee-Yang, W. Ciblak, M. A. (2002). Comparative evaluation of NCCLS M27-A and EUCAST broth microdilution procedures for antifungal susceptibility testing of Candida species. Antimicrob Agents Chemother; 46:3644-3647.

https://doi.org/10.1128/AAC.46.11.3644-3647.2002

Cuenca-Estrella, M. Moore, C. B. Barchiesi, F. (2003). Multicenter evaluation of the reproducibility of the proposed antifungal susceptibility testing method for fermentative yeasts of the Antifungal Susceptibility Testing Subcommittee of the European Committee on Antimicrobial Susceptibility Testing (AFST-EUCAST). Clin Microbiol Infect; 9:467-474.

https://doi.org/10.1046/j.1469-0691.2003.00592.x

Das, P. P. Saikia, L. Nath, R.and Phukan, S. K. (2016). Species distribution and antifungal susceptibility pattern of oropharyngeal Candida isolates from human immunodeficiency virus infected individuals; Indian J Med Res 143:495- 501

https://doi.org/10.4103/0971-5916.184288

El-Mashad, N. and Mahmoud, M. T. (2011). Commercial tests for in vitro antifungal susceptibility testing of Candida species compared to standard (NCCLS) broth microdilution International Journal of Medicine and Medical Sciences 3(4)100- 104

Espinel-Ingroff, A, Pfaller, M, Messer, S. A. (1999). Multicenter comparison of the sensititre YeastOne Colorimetric Antifungal Panel with the National Committee for Clinical Laboratory standards M27-A reference method for testing clinical isolates of common and emerging Candida spp., Cryptococcus spp., and other yeasts and yeast-like organisms. J Clin Microbiol; 37:591- 595.

https://doi.org/10.1128/JCM.37.3.591-595.1999

George, P., Deborah, A. Heather, K., Abdulrahim, I. (2014).Time-Kill Assay and Etest Evaluation for Synergy with Polymyxin B and Fluconazole against Candida glabrata; Antimicrobial Agents and Chemotherapy p. 58(10): 5795- 5800.Hajjeh, R. A., Sofair, A. N. Harrison, L. H. Lyon, G. M. Arthington- Skaggs, B. A. Mirza, S. A. Phelan, M. Morgan, J. Lee-Yang, W. Ciblak, M. A. Benjamin, L. E. Sanza, L. T. Huie, S. Yeo,

https://doi.org/10.1128/AAC.03035-14

Kanafani, Z. A. Perfect, J. R. (2008). Antimicrobial resistance: resistance to antifungal agents: mechanisms and clinical impact. Clin Infect Dis; 46:120.

https://doi.org/10.1086/524071

Kao, A. S., Brandt, M. E. Pruitt, W. R. Conn, L.A. Perkins, B. A. Stephens, D. S.W. Baughman, A. L. Reingold, A. L. Rothrock, G. A. Pfaller, M. A. Pinner, R.W. and Hajjeh. R. A. (2001). The epidemiology of candidemia in two United States cities: results of a population-based active surveillance. Clin. Infect. Dis. 29:1164-1170.

https://doi.org/10.1086/313450

Lyon, M. G. (2011). Sulaiman Karatela, Susan Sunay, and Yaffa Adiri Antifungal Susceptibility Testing of Candida Isolates from the Candida Surveillance Study_ Journal of Clinical Microbiology 48:1270-1275, No. 4 0095-1137/10/$12.00 doi:10.1128/JCM.02363-09

https://doi.org/10.1128/JCM.02363-09

Matar, M. J. Ostrosky-Zeichner, L. Paetznick, V. Jose, L. Rodriguez, R. Chen, E. and John, H. R. (2003). Correlation between E-Test, Disk Diffusion, and Microdilution Methods for Antifungal Susceptibility Testing of Fluconazole and Voriconazole Antimicrobial Agents And Chemotherapy; American Society for Microbiology. 47:1647-1651

https://doi.org/10.1128/AAC.47.5.1647-1651.2003

National Committee for Clinical Laboratory Standards (2002). Reference method for broth dilution antifungal susceptibility testing of yeasts. Document M27-A2. Wayne, PA: NCCLS,

Negri, M. Henriques, M. Terezinha, I. E. Svidzinski, Paula, C. R. and Oliveira,R. (2009). Correlation Between Etests, Disk Diffusion, and Microdilution Methods for Antifungal Susceptibility Testing of Candida Species From Infection and Colonization; Journal of Clinical Laboratory Analysis 23:324-330

https://doi.org/10.1002/jcla.20337

Nishikaku, A. S., Melo, A. S. A. & Colombo, A.L. (2010). Geographic trends in invasive candidiasis. Curr Fungal Infect Rep 4:210-218.

https://doi.org/10.1007/s12281-010-0033-7

Pfaller, M. A., Castanheira, M., Lockhart, S. R., Ahlquist, A. M., Messer, S. A. & Jones,

R. N. (2012a). Frequency of decreased susceptibility and resistance to echinocandins among fluconazole- resistant bloodstream isolates of Candida glabrata. J Clin Microbiol 50:1199-1203.

https://doi.org/10.1128/JCM.06112-11

Pfaller, M. A, Diekema, D. J. (2012). Progress in antifungal susceptibility testing of Candida species. By use of clinical and laboratory standards institute broth microdilution methods, 2010 to 2012. JClin Microbiol. 50:2846-56.

https://doi.org/10.1128/JCM.00937-12

Pfaller, M. A., Jones, R. N. Doern, G. V. Sader,H. S. Messer, S. A. Houston, A. Coffman, S. and Hollis. R. J. (2000). Bloodstream infections due to Candida species: SENTRY antimicrobial surveillance program in North America and Latin America, 1997-1998. Antimicrob. Agents Chemother. 44:747- 751.

https://doi.org/10.1128/AAC.44.3.747-751.2000

Punithavathy, P. M., Nalina, K. (2012). Antifungal susceptibility testing of Candida tropicalis biofilms against fluconazole using calorimetric indicator resazurin.; Indian Journal of Pathology and Microbiology; 55(1):72-74

https://doi.org/10.4103/0377-4929.94861

Rodriguez-Tudela, J. L. Barchiesi, F, Bille,J. (2003). Method for the determination of minimum inhibitory concentration (MIC) by broth dilution of fermentative yeasts. Clin Microbiol Infect,; 9: I-VIII.

https://doi.org/10.1046/j.1469-0691.2003.00789.x

Rosco Diagnostica, (2011). Susceptibility testing of yeast. Agar diffusion method with neosensitibs using meuller Hinton agar;Pp 8

Sumana, M.N. Satya, S. B. Kademani, N. D. Madhuri, M. J. (2017). speciation and antifungal susceptibility testing of candida isolated from urine; Indian Journal of Medical Research and Pharmaceutical Sciences 4(9)1-4

Trick, W. E., Fridkin, S. K. Edwards, J. R. Hajjeh, R. A. and Gaynes. R. P. ( 2002). Secular trend of hospital acquired candidemia among intensive care unit patients in the United States during 1989-1999. Clin. Infect. Dis. 35: 627-630.

https://doi.org/10.1086/342300

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Published

30-06-2020

How to Cite

Sule, H., Kumurya, A. S., & Ibrahim, A. (2020). Antibiogram of Candida Species using Different Susceptibility Testing Techniques: A Systematic Review. UMYU Journal of Microbiology Research (UJMR), 5(1), 36–42. https://doi.org/10.47430/ujmr.2051.006

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